Authors: Brynolf I.
Title: A histological and roentgenological study of the periapical region of human upper incisors.
Journal: Odonto Revy Suppl
Date: Jan 1967
Citation: Supplement 11
Category: Success and Failure
Evidence-based Ranking: 4
Purpose/Objectives: To compare the histological and roentgenological appearance of periapical changes in an attempt to find out whether the extent of histological changes are reflected in conventional roentgenograms.

Materials & Methods: 292 maxillary incisors obtained from cadavers were used. Immediately after the roentgenograms were taken, the tips of the roots were removed with a trepan. The specimens were fixed and prepared histologically. Specimens were then divided into 3 groups depending on the inflammatory cells in apical tissue, type of periapical marrow, and the shape of apical soft tissue. Group N (normal group), without inflammatory cells in apical soft tissue. Group M (marginal group), with very few scattered inflammatory cells and increased width of apical soft tissue. Group P, with mild to severe chronic inflammation cells in the apical soft tissue. Details in the roentgenograms were defined, graded and recorded in the same way as in the histological study.

Results: It was found that the changes in the roentgenological groups are very similar with those in the histological groups.

AuthorÂ’s Conclusion: Careful examination of high quality roentgenograms of the periapical areas of the upper incisors allows differentiation between histologically normal and pathological cases, and classification of different types and stages of histologic periapical lesions.

ReviewerÂ’s Comments: The article attempts to distinguish histologically normal from pathological cases with well defined roentgenolgical changes.