- Authors: Bergenholtz G.
- Title: Inflammatory response of the dental pulp to bacterial irritation.
- Journal: J Endod
- Date: Mar 1981
- Citation: 7(3):100-4
- Category: Endodontic Biology, Histology and Physiology
- Evidence-based Ranking: 5
- Purpose/Objectives: A summary of the literature involving the pulpal response to bacteria and the toxins they produce.
Results: Bacterial irritants in the carious process The literature supports the fact that bacteria and the toxins they produce initiate an inflammatory reaction in the pulp and that dentine tubules provide a route for these irritants to the pulp.
Pulpal effect of the bacterial products Bacteria found in caries and plaque have the capacity to initiate PMN infiltration and abscess formation.
Mechanisms of pulp tissue damage Pulpal response to bacteria can result in chemotaxis of cell mediated and humoral immunological cells, complement activation, and vascular changes.
Healing capacity of the pulp The pulp has excellent healing capacity. Inflammatory response can vary from minor to severe, reparative dentin formation can slow the effect of caries, localized abscesses can heal.
Authors Conclusion: The response of the pulp to bacterial infection is a multifactorial process with excellent healing capacity.
Validity of Conclusion: Valid, however, some literature on cultures from carious bacteria may not be true due to limited sampling techniques at the time.